Case Study of Microphysiological System Models for ILD: Developing In Vitro Assays for Evaluating ADC Lung Safety

• Leveraging complex in vitro models to evaluate ADC-induced lung toxicity
• Building in vitro tools for high-throughput compound screening
• Pending relevance to pathogenesis of ILD, high-throughput imaging-based assays may potentially be incorporated into a holistic screening approach to differentiate ADCs and guide selection of safer compounds

Speakers:

Ronnie Yeager

Research Fellow, Emerging Therapeutic Platforms (Development Sciences)

AbbVie