Holistic In Silico Evaluation of Development Liability Risk in Miniproteins

• Understand how immunogenicity, stickiness, and other liabilities frequently cannot be solved in isolation without worsening other properties
• Explore how In silico predictors can be tuned to not only guide efforts to verify predicted risks but also unify potential solutions in sequence space
• Discover a unified framework for evaluating and allocating effort to solving developmental liabilities, including toxicity, can significantly accelerate development efforts

Speakers:

Frank Teets

Head of Computation

AI Proteins