Understanding Clinically Relevant Dose Selection for ADCs Using Toxicology Data

• Review the ADC landscape to understand translatability of ADC platform toxicities
• Integrate off-target and on-target findings in cynomolgus monkey
• Therapeutic window prediction by selecting appropriate preclinical efficacy models and dosing schedules

Speakers:

Jutta Deckert

Vice President, Research & Development

Iksuda Therapeutics