Raghu Tadagavadi
Executive Director, Nonclinical Development & Safety Century Therapeutics
Seminars
Wednesday 13th May 2026
Translating Preclinical Toxicology & Efficacy Insights into a Successful IND
4:00 pm
- Evaluate in vitro discovery and investigative toxicology in cell therapy platforms to define target biology, evaluate therapeutic liabilities, and establish early human relevance
- Review fit-for-purpose in vivo models in cell therapies to integrate safety with efficacy, PK, and biodistribution, while acknowledging species differences and model limitations
- Discover a strategy integrating in vitro and in vivo data to address safety liabilities while leveraging efficacy strengths for a regulatory-aligned IND in cell therapy
